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Reviews, Side Effects & Evidence Berberine patches have emerged as a novel transdermal delivery system, marketed as an alternative to oral berberine supplements for blood glucose regulation and metabolic health

Knudsen is a scientist at the Danish drug maker Novo Nordisk, which harnessed insights by Habener and Mojsov to create the blockbuster drugs Ozempic for diabetes and Wegovy for obesity

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Bulk-forming laxatives such as ispaghula husk (Fybogel) and sterculia (Normacol) are generally recommended as first-line treatment for constipation with hard stools according to NICE Clinical Knowledge Summaries